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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Catecholaminergic polymorphic ventricular tachycardia ： ウィキペディア英語版 Catecholaminergic polymorphic ventricular tachycardia Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) is a rhythm disorder of the ventricles of the heart that occurs in genetically predisposed individuals. Synonyms: Familial Polymorphic Ventricular Tachycardia (FPVT), Catecholamine-Induced Polymorphic Ventricular Tachycardia. Thought to affect as many as one in ten thousand people, it is estimated to cause 15% of all unexplained sudden cardiac deaths in young people. First recognized in 1975, this condition is due to mutations in genes encoding a calcium channel or proteins related to this channel. All mutated proteins participate in the regulation of calcium ion flow in and out of the sarcoplasmatic reticulum of cardiac cells. Therefore reduced electrical stability of cardiomyocytes may cause the heart to enter a life-threatening state of ventricular arrhythmia as response to the natural release of catecholamines from nerve endings on the heart muscle and from the adrenal glands into the circulation. This rhythm disturbance prevents the heart from pumping blood appropriately. Ventricular tachycardia may self-terminate or degenerate into ventricular fibrillation, causing sudden death unless immediate cardiopulmonary resuscitation is applied. ==Signs and symptoms== The most common symptom is dizziness or syncope which often occurs during exercise or as a response to emotional stress. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Catecholaminergic polymorphic ventricular tachycardia」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.